Expiratory Aerosol pH is a Driver of the Persistence of Airborne Influenza A Virus

To mitigate the spread of a viral disease, it is crucial to understand factors that influence airborne virus transmission. However, micro-environment which exposed in expiratory aerosol particles highly complex. The relative humidity, particle size and composition, air composition affect infectivity by modulating salt organic concentrations within particle, as well phase state. A parameter has been overlooked pH. Several viruses are sensitive acidic pH; for example, inactivation influenza becomes very fast at pH 5.5 below, threshold quickly reached an exhaled typical indoor environment. Therefore, acidity plays significant role controlling persistence airborne, acid-sensitive such virus, control could be applied limit risk